http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104711319-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f486b546c8539873c267448bfe812153 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2013-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10dec3d2ad80132d5bd84c04658cf9ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_351754d4d10c5e710b1c08bc57335373 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c159c6f7248b8b99eef3e5ae97bd3201 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa0817b211651d05dd88180e4b2431d6 |
publicationDate | 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104711319-A |
titleOfInvention | Alzheimer disease early-stage lesion PS-2 gene mRNA level in-situ hybridization detection kit |
abstract | The invention discloses an in-situ hybridization detection kit, which comprises a hybridization probe and a marker, and further discloses a method utilizing the in-situ hybridization detection kit to detect the PS-2 gene mRNA, which is closely related with the Alzheimer disease (AD) early-stage pathologic evolution. The method comprises the following steps: (1) under a condition that a hybridization probe and a target sequence can form a stable hybridization complex, contacting RNA to be detected in a substrate with a hybridization probe so as to form a hybridization complex; (2) detecting the obtained hybridization complex. The provided kit and detection method can detect the expression function of PS-2 gene in the mRNA level, can detect the cancer in an earlier stage compared with the medical imaging technology and conventional clinical biochemical index detection, can achieve real mRNA level screening in the early-stage lesion of AD so as to prevent and treat AD in advance, moreover, have the advantages of simpleness, convenience, and low cost, and thus are convenient to promote and use in hospitals. |
priorityDate | 2013-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.