http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104710625-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G61-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate | 2015-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104710625-B |
| titleOfInvention | A kind of near-infrared response degradable water soluble copolymer and its high-efficiency synthesis method |
| abstract | The present invention is a kind of near-infrared response degradable water soluble copolymer and its high-efficiency synthesis method, synthesized by Sonogashira coupling reaction and a kind of new there is water solublity degradable polymer, micelle can be self-assembled in water, after 800nm light irradiation, in main chain, benzyne benzene structure has the effect of two-photon absorption, absorb near infrared light emitting ultraviolet light, so that absorbing the main chain ester bond functional group fracture of ultraviolet light, polymer micelle is destroyed.This new polymerss can be used as the carrier of medicament transport, for wrapping up some hydrophobic drugs, because polymer lateral chain is connected to Polyethylene Glycol (PEG), so the micelle being formed has good water solublity and biocompatibility, can be used for cell and the carrier of live body medicament transport.And this polymer micelle has been carried out with the sign such as ultra-violet absorption spectrum, gel permeation chromatography, transmission electron microscope, dynamic light scattering, have studied its molecular size range and micelle size and the light degradation property of near-infrared response. |
| priorityDate | 2015-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.