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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-0053
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00
filingDate 2015-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104710494-B
titleOfInvention Production technology of hydrocortisone acetate
abstract The invention discloses a production technology of hydrocortisone acetate, which belongs to the technical field of chemical pharmacy. The technology employs reaction of hydrocortisone and acetic anhydride to prepare the product, a reaction of hydrocortisone and acetic anhydride is carried out in a dipolar aprotic solvent, an alkali salt acetate is taken as a catalyst, the reaction is carried out under nitrogen or inert gas protection, and the dipolar aprotic solvent is dimethyl formamide or dimethyl sulfoxide. The technology has the advantages of high yield and good product quality.
priorityDate 2015-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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