http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104693259-B

Outgoing Links

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0033
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-621
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-618
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00
filingDate 2015-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104693259-B
titleOfInvention A kind of aspirin Caudatin. esters derivative compound and its preparation method and application
abstract The present invention relates to a kind of aspirin Caudatin. esters derivative compound and its preparation method and application, belong to technical field of medicine synthesis. The problem solved is to develop new compound to make have anti-tumor activity. Thering is provided a kind of aspirin Caudatin. esters derivative compound and its preparation method and application, the method includes under the effect of dehydrant, makes Caudatin. and aldehydes or ketones class react, generates 8,14-O-different alkylidene Caudatin .s; Again under the effect of catalyst so that it is react with acetyl-salicylic derivate, after terminating, slough protection base in acid condition, obtain end product aspirin Caudatin. esters derivative compound. The compound of the present invention has dual-target and acts on tumor cell, it is achieved better antitumous effect, and has raw material and be easy to get, the advantage that technique is simple and easily operated, it is possible to for antitumor drug.
priorityDate 2015-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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