http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104693259-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0033 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-621 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-618 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 |
filingDate | 2015-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104693259-B |
titleOfInvention | A kind of aspirin Caudatin. esters derivative compound and its preparation method and application |
abstract | The present invention relates to a kind of aspirin Caudatin. esters derivative compound and its preparation method and application, belong to technical field of medicine synthesis. The problem solved is to develop new compound to make have anti-tumor activity. Thering is provided a kind of aspirin Caudatin. esters derivative compound and its preparation method and application, the method includes under the effect of dehydrant, makes Caudatin. and aldehydes or ketones class react, generates 8,14-O-different alkylidene Caudatin .s; Again under the effect of catalyst so that it is react with acetyl-salicylic derivate, after terminating, slough protection base in acid condition, obtain end product aspirin Caudatin. esters derivative compound. The compound of the present invention has dual-target and acts on tumor cell, it is achieved better antitumous effect, and has raw material and be easy to get, the advantage that technique is simple and easily operated, it is possible to for antitumor drug. |
priorityDate | 2015-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.