| abstract |
The invention discloses a kind of palladium chtalyst synthesis alpha-aromatic, heteroaryl or alkenyl-α, α-difluoro allylic structure methods.Specifically, method of the invention is in the presence of alkali and/or ligand, to synthesize formula C compound, compound is defined in the specification by formula A compound and formula B compound under the catalysis of palladium salt.This method has the advantages that raw material is simple, is easy to get, and catalyst amount is few, wide application range of substrates, easy to operate, reaction efficiency is high, product obtained biological medicine, pesticide and in terms of suffer from and be widely applied. |