http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104689321-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 |
filingDate | 2013-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104689321-B |
titleOfInvention | Curcumin long-circulating nanoliposome carrier of enoxolone mediation and preparation method thereof |
abstract | The invention provides curcumin long-circulating nanoliposome carrier of a kind of enoxolone mediation and preparation method thereof, the nano-lipid carrier is prepared by curcumin, glycerin monostearate, caprylic/capric triglyceride, enoxolone phospholipid derivative, soybean lecithin for injection and the Strearate of Polyoxyethylene 40, first by lipid and curcumin heating water bath to 75 DEG C, adding absolute ethyl alcohol dissolves it, and rotary evaporation removes absolute ethyl alcohol and is used as oil phase;Water for injection is added in the Strearate of Polyoxyethylene 40, heating water bath is used as aqueous phase to 75 ± 2 DEG C after ultrasonic agitation is uniform;Aqueous phase is added dropwise in synthermal oil phase under magnetic agitation, colostrum is made in constant temperature stirring 5min, ultrasonic cell disruptor ultrasonic disperse 5min is used while hot, 0.22 μm of miillpore filter is crossed, room temperature ice-water bath cooling and solidifying obtains the curcumin long-circulating nanoliposome carrier dispersion liquid of enoxolone mediation. |
priorityDate | 2013-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.