http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104688674-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-26 |
| filingDate | 2013-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104688674-B |
| titleOfInvention | A kind of preparation method of bemegrid parenteral solution |
| abstract | The invention provides a kind of preparation method of bemegrid parenteral solution.The present invention is by improving preparation method：Terminal sterilization condition is by 100 DEG C, and 45min is improved to 116 DEG C, 30 45min；With liquid water for injection temperature by being improved to water temperature more than 90 DEG C as 70 85 DEG C.By testing inspection, the Sterility testing of product has reached regulation requirement, and relevant material index has also declined.So as to preferably reduce the quality risk of product and the drug risk of patient.After accelerated experiment and long-term stable experiment, show after using new method of the present invention, bemegrid parenteral solution sterility test, the bemegrid parenteral solution YBH03112012 standards for reaching about indices such as material, contents state food and drug administration, have reached good effect.The inventive method is simple, does not increase new cost, is suitable for scale industrialized production, there is larger application value. |
| priorityDate | 2013-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.