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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-02
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70
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filingDate 2015-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104673813-B
titleOfInvention A kind of ophiobolin class compound parent nucleus synthetic gene AuOS and its application
abstract The invention discloses a kind of ophiobolin class compound parent nucleus synthetic gene AuOS And its application, belong to genetic engineering field.The ophiobolin class compound parent nucleus synthetic gene AuOS From aspergillus ustus 094102, the amino acid sequence of the AuOS albumen of its gene order, cDNA sequence and coding is respectively as shown in SEQ ID NO.1 3.AuOS albumen has the function that the extension of catalysis substrate chain length and structure are cyclized, and the albumen can be using this 4 kinds of compounds of DMAPP, GPP, FPP and GGPP as substrate and IPP reaction generation ophiobolin class compound parent nucleus.Present invention firstly discovers that aspergillus ustus 094102 AuOS Gene, its encoding proteins have the function that the extension of catalysis substrate chain length and structure are cyclized, can be using DMAPP as substrate de novo formation ophiobolin class compound parent nucleus, preparation and its research of biosynthesis pathway available for ophiobolin class compound.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108486073-A
priorityDate 2015-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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