http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104672128-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_226fa86f9790e799a44846e2f6319e98 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-64 |
| filingDate | 2015-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ab481d9ef51aedfd83967588d073bbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d5a7993f5e3fc6b2cb71b1781ec0f3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4787a53e593d43297d10603e09be084c |
| publicationDate | 2015-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104672128-A |
| titleOfInvention | Flexible bispyridine derivative 6-methoxy-2-pyridylmethylpyridine and its synthesis method |
| abstract | The invention discloses a flexible bispyridine derivative 6-methoxy-2-pyridine methylene pyridine and a synthesis method thereof. The method is as follows: under the protection of N2 , add 2-methyl-2-pyridine to a three-necked flask 6-Methoxypyridine and tetrahydrofuran, add n-butyllithium dropwise, stir for 45min, the system solution gradually changes from light yellow to orange yellow, slowly raise the temperature to -20°C, add 2-fluoropyridine, reflux for 6h, add 100mL water to quench Extinguish the reaction, separate the layers, extract the aqueous layer with ethyl acetate or dichloromethane two to four times, dry the organic layer with anhydrous sodium sulfate or calcium chloride for 1 to 3 hours, spin the organic solvent to dry, and pass through a period of alumina column, a yellow oily liquid was obtained. The present invention synthesizes an asymmetric flexible bispyridine compound, and introduces a methoxy group at the 2-position of pyridine to facilitate the conversion between functional groups, so as to synthesize bispyridine derivatives containing hydroxyl substituent groups, Thus, crystalline network complexes with different spatial configurations are constructed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111303446-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111303446-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105061400-A |
| priorityDate | 2015-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.