http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104666322-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 |
filingDate | 2015-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104666322-B |
titleOfInvention | New uses of 24‑acetyl alisol F |
abstract | The present invention provides a new application of 24-acetyl alisitol F (ALI), which can increase the accumulation of doxorubicin (DOX) in cells, promote the entry of doxorubicin into the nucleus, and then Significantly promote the early apoptosis of MCF-7/ADR cells (human breast cancer-doxorubicin-resistant cells), which has important drug development value in the preparation of anti-tumor drugs, prepared from 24-acetyl alisol F and doxorubicin The composition of the invention can effectively increase the sensitivity of the anticancer drug doxorubicin due to the effect of 24‑acetyl alisol F, and reduce the side effects of the existing chemotherapy drugs while improving the curative effect of chemotherapy. |
priorityDate | 2015-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.