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Predicate Object
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58
filingDate 2015-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104666322-B
titleOfInvention New uses of 24‑acetyl alisol F
abstract The present invention provides a new application of 24-acetyl alisitol F (ALI), which can increase the accumulation of doxorubicin (DOX) in cells, promote the entry of doxorubicin into the nucleus, and then Significantly promote the early apoptosis of MCF-7/ADR cells (human breast cancer-doxorubicin-resistant cells), which has important drug development value in the preparation of anti-tumor drugs, prepared from 24-acetyl alisol F and doxorubicin The composition of the invention can effectively increase the sensitivity of the anticancer drug doxorubicin due to the effect of 24‑acetyl alisol F, and reduce the side effects of the existing chemotherapy drugs while improving the curative effect of chemotherapy.
priorityDate 2015-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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