http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104666278-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 |
| filingDate | 2015-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104666278-B |
| titleOfInvention | A kind of preparation and application with light-operated release function magnetic target medicine carrier |
| abstract | The present invention relates to a kind of preparation and application with light-operated release function magnetic target medicine carrier, and in particular to the preparation and application of the temperature sensitive chorion structure carrier with light-operated release function based on ferroso-ferric oxide, belongs to diagnosis and treatment agent field；The present invention is by magnetic iron oxide Surface coating silica, utilize temperature sensing material N N-isopropylacrylamides (PNIPAM) and N vinyl pyrrolidones (NVP) crosslinking coated silica, corrosion is carried out to silica by NaOH again and forms chorion structure carrier, the carrier phase-change temperature is about 41 DEG C, for loading anticancer drugs, doxorubicin；The application is that carrier has good magnetic targeted function, in near-infrared laser (NIR, the nm of wavelength 808) the lower generation photo-thermal effect of irradiation, induce temperature sensitive carrier to produce phase transformation at about 41 DEG C and discharge medicine, carrier prepared by the present invention is by magnetic resonance imaging, the functions such as photoacoustic imaging are integrated in one, and good application effect is shown in cell experiment, are a kind of good pharmaceutical carriers. |
| priorityDate | 2015-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.