http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104651488-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
filingDate | 2014-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104651488-B |
titleOfInvention | Detect the Amplification thing and quick detection kit of chromosome aneuploid numerical abnormality |
abstract | The present invention relates to the Amplification thing of detection chromosome aneuploid numerical abnormality and quick detection kit, belong to biological technical field.The present invention can be with No. 21 chromosomes of augmentation detection 8,6 No. 18 chromosomes, 6 No. 13 chromosomes STR bit point related with 3 X chromosomes, while 4 sex sites of augmentation detection in the amplification system that height is combined.And above-mentioned all sites are expanded by quantitative fluorescence PCR (QF PCR) technology, 21,18,13, X and Y chromosome aneuploid numerical abnormality are detected.Kit of the present invention, detection cycle is short, and result can be just can obtain within 5 hours after obtaining sample, sensitivity is high, and detection every time only needs the other DNA of nanogram level, the amount of DNA contained by equivalent to 100 cells, therefore the sample size needed is few, it is necessary to which 1 2ml amniotic fluid can meet demand.Because sensitivity is higher, the chimera that heterotrimeric cell accounts for more than 10% can be just detected. |
priorityDate | 2014-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.