http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104650208-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-465 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
| filingDate | 2015-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104650208-B |
| titleOfInvention | Derived peptide of one breeder derived antimicrobial peptide and its preparation method and application |
| abstract | The present invention provides derived peptide of a breeder derived antimicrobial peptide and its preparation method and application.The derived peptide, sequence is as shown in SEQ No.1.20 amino acid of present invention interception chicken source AvBD4 leader peptides, the cysteine of leader peptide the 5th is substituted with charge residue lysine respectively, the phenylalanine of the 6th, 7,12, while by the terminal-carboxy amidation of antibacterial peptide, one positive charge of increase is improving the stability of antibacterial peptide.MGW21 crude products are obtained using solid-state chemical reaction method method；The polypeptide of synthesis is purified and identified using reversed-phase high performance liquid chromatography and electrospray mass spectrometry.Application of the antibacterial peptide in treatment gram-positive bacteria or gram positive bacterial infection disease medicament is prepared.The antibacterial peptide is amphipathic good, and compared with antibiotic and Melittin, its bacteriostatic activity is high, and cytotoxicity is low. |
| priorityDate | 2015-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.