abstract |
The invention belongs to the technical field of medicines, and particularly relates to an aromatic heterocyclic carboxylic acid derivative GPR40 receptor agonist shown in a general formula (I) in the specification, and pharmaceutically acceptable salts, esters or stereo isomers thereof, wherein R1, R2, R3, R4, R5 and X are defined as those described in the specification. The invention also relates to preparation methods, pharmaceutical preparations and pharmaceutical compositions of the compounds, and applications of the compounds and the pharmaceutical compositions in preparing drugs as GPR40 receptor agonists for preventing and/or treating diabetes. |