http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104649917-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08 |
| filingDate | 2015-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104649917-B |
| titleOfInvention | A kind of three-membered ring derivative containing beta-amino ester and synthetic method thereof and application |
| abstract | The present invention relates to a kind of three-membered ring derivative containing β amino ester and chemical synthesis process thereof, with cyclopropyl diazonium compound, benzylalcohol and imines as raw material, with Molecular sieve is water absorbing agent, with chirality BINOL phosphoric acid and rhodium acetate as co-catalyst, with organic solvent as solvent, obtains product through single step reaction.Synthetic method of the present invention has atom economy, high selective advantage, and reaction condition is gentle, safety simple to operate.The three-membered ring derivative containing β amino ester that the present invention prepares is important chemical industry and medicine intermediate, and has biologically active, it is adaptable to the application and preparation of antineoplastic. |
| priorityDate | 2015-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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