http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104644614-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 |
| filingDate | 2015-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104644614-B |
| titleOfInvention | A kind of support type hemoglobin compositions and preparation method thereof |
| abstract | The present invention relates to a kind of support type hemoglobin compositions and preparation method thereof, the preparation method comprises the following steps：(1) carrier PEG-PLA hydroxyacetic acid block copolymer is dissolved in organic solvent, then it mixed with the aqueous solution of hemoglobin, ultrasound, form colostrum；(2) aqueous solution of surfactant is added into colostrum obtained by step (1), mixing, ultrasound, forms emulsion；(3) organic solvent is removed, centrifugation, obtains support type hemoglobin compositions.The present invention prepares support type hemoglobin compositions using double newborn methods, and method is simple and easy, and the support type hemoglobin compositions being prepared, which possess to take, puts oxygen function, there is approximate rheological behavior with whole blood, stability is high, possesses good blood compatibility, will not cause erythrocyte aggregation；The carrier material not only abundant raw material of the present invention, and with low cost, it is biodegradable, good biocompatibility and bioaffinity, it is nontoxic, be easy to the advantages that chemical modification. |
| priorityDate | 2015-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.