| abstract |
The subject matter of this document relates to carbazole-containing sulfonamide derivatives of formula I and their pharmaceutically acceptable salts or hydrates, wherein the variables R 1 , R 2 , R 3 , R 4 , R 5 , R 6 are described accordingly , R7 , A, B, C, D, E, F, G, H, a and b. Also provided are pharmaceutical compositions comprising compounds of formula I for the treatment of Cry-mediated diseases or conditions, such as diabetes, obesity, metabolic syndrome, Cushing's syndrome, and glaucoma. |