http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104630123-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-75 |
| filingDate | 2013-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104630123-B |
| titleOfInvention | Bacillus licheniformis expressive host |
| abstract | The invention discloses bacillus licheniformis the host strain BL10, deposit number CCTCCNO of a kind of polygene deletion：M2013400.The host strain derives from bacillus licheniformis WX 02, has partially or completely lacked 10 genes.This 10 genes are that (mpr encodes extracellular metalloproteinases to 8 protease genes respectively；Vpr, encoding serine protease；AprX, intracellular serine protease；Epr encodes small extracellular protease；Bpr, coding bacillus peptase F；WprA, the protease of coding and cell wall-bound；AprE encodes extracellular alkaline serine protease；BprA, coding bacillus peptase F) and 2 exocytosis protein gene (hag, coding flagellins；AmyL encodes alpha amylase).BL10 can reduce degradation of the protease to target protein entirely without extracellular protease activity.When expressing target protein using the expressive host, expression quantity higher, the host strain is conducive to enhance the expression of albumen. |
| priorityDate | 2013-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 162.