http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104628737-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22 |
| filingDate | 2015-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104628737-B |
| titleOfInvention | Two kinds of 9 nitrocamptothecins of novel crystal forms and preparation method thereof |
| abstract | The invention discloses two kinds of 9 nitrocamptothecins of novel crystal forms and preparation method thereof.In powder x-ray diffraction spectrum of the copper target as radiation source is used, crystal formation I has characteristic peak for 5.8 ± 0.1,7.4 ± 0.1,8.8 ± 0.1,10.5 ± 0.1,11.3 ± 0.2,11.7 ± 0,15.7 ± 0.2,17.8 ± 0.1,18.7 ± 0.1,21.1 ± 0.1,24.1 ± 0.1 and 26.2 ± 0.1 degree in the θ of the angle of diffraction 2.Crystal formation II has characteristic peak for 6.1 ± 0.2,6.7 ± 0.1,7.5 ± 0.2,9.4 ± 0.1,11.4 ± 0.2,12.4 ± 0.1,14.1 ± 0.1,15.1 ± 0.1,17.6 ± 0.1,19.7 ± 0.1,22.6 ± 0.1,23.8 ± 0.1,25.2 ± 0.1,27.3 ± 0.1 and 29.2 ± 0.2 degree in the θ of the angle of diffraction 2.The preparation method of two kinds of crystal formations is all based on super-critical anti-solvent technology.Prepare the New crystal form I of 9 nitrocamptothecins and II solubility is all higher than existing crystal formation, heat endurance is also superior to existing crystal formation. |
| priorityDate | 2015-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.