http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104628547-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-16 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-753 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-64 |
| filingDate | 2015-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104628547-B |
| titleOfInvention | A kind of synthetic method of medicine intermediate difluoromethoxy based compound |
| abstract | The invention provides the synthetic method of difluoromethoxy based compound shown in a kind of following formula (I), Described method includes: in a solvent, and under catalyst, organic ligand and alkali exist, formula (II) compound and formula (III) compound react, thus obtaining formula (I) compound, Wherein, R is H, C 1 -C 6 Alkyl, benzyl, halogen or nitro, described method is by the mutually collaborative of suitable catalyst, organic ligand, alkali and solvent and/or combination, it is achieved thereby that the efficient difluoro-methoxy of reaction substrate, difluoro-methoxy substituted compound can be obtained with high yield, the brand-new synthetic method of such intermediate is provided for field of medicaments, it is the very valuable novel technological method of one, there is the prospect that is extremely widely applied. |
| priorityDate | 2015-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.