http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104623737-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 |
filingDate | 2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104623737-B |
titleOfInvention | A kind of personalized tissue recovery support of achievable pulsed sustained release and preparation method thereof |
abstract | The present invention provides a kind of personalized tissue recovery support for the wound repair such as bone, cartilage, defect of skin field, it is molded by three-dimensional printing technology, including a matrix and the multiple sustained-release micro-spheres being scattered in the matrix, the sustained-release micro-spheres have includes the three-decker of stratum nucleare, intermediate layer and outer layer, and growth factor and/or medicine are loaded in the stratum nucleare and outer layer of the sustained-release micro-spheres.According to therapentic part feature, the hole of described matrix can further cast degradable macromolecule compound hydrogel or degradable macromolecule/inorganic matter hybridized hydrogel, and then be molded by frozen drying method.The present invention also provides a kind of preparation method of personalized tissue recovery support.Personalized tissue recovery support of the invention uses the sustained-release micro-spheres of three-decker, with good biocompatibility and degradability, for the pulsed sustained release growth factor and/or medicine, effect of sustained release steady in a long-term is reached, be conducive to extending the sustained release cycle of growth factor and/or medicine. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2763138-C1 |
priorityDate | 2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.