http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104623635-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 |
| filingDate | 2015-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104623635-B |
| titleOfInvention | Pharmaceutical composition for preventing and treating cerebral ischemia |
| abstract | The invention discloses injection for preventing and treating cerebral ischemia. The injection comprises rhEGF (Recombinant Human Epidermal Growth Factor), aspirin, an antioxidant, a cosolvent and a pH regulator. The pharmacological research shows that the medicine can pass through blood brain barrier to be mainly distributed in cerebral hemisphere, brainstem and the like, takes spasmolysis effect on vascular smooth muscle, and can expand small vessels, reduce resistance of blood vessels of brain, increase cerebral blood flow, protect endothelial cells and improve micro-circulation. The injection has the functions of increasing cerebral perfusion of distant sites after MCAO (middle cerebral artery occlusion), resisting apoptosis, protecting nerve cells in the distant sites, and reducing the diaschisis damage to brain tissues in the distant sites due to interruption of conduction paths of nerve fibers; therefore, the injection has the effect of reducing the disordered brain function in the distant sites and has a certain effect in clinical prognosis after relieving stroke. |
| priorityDate | 2015-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.