http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104622813-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 |
filingDate | 2015-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104622813-B |
titleOfInvention | A kind of nanoparticle formed based on host-guest interaction and its preparation method and purposes |
abstract | A kind of poly epsilon caprolactone lactone using an end group as adamantane or poly- D, L lactides are hydrophobic core, the beta cyclodextrin of more PVP macromolecular chains passes through the nano-particle that adamantane is formed with beta cyclodextrin host-guest interaction as hydrophilic segment using hydroxyl modified on multiple 6 C of glucose.It is characterized in that:Its surface is hydrophilic PVP, and inside is hydrophobic poly epsilon caprolactone lactone or poly- D, L lactide, and two parts are connected by the host-guest interaction of adamantane and beta cyclodextrin.It is 2000~10000g/mol to be connected to the poly epsilon caprolactone lactone of adamantane or poly- D, L lactide molecular weight, and beta cyclodextrin can modify more PVPs, and the molecular weight of every PVP is 1000~10000g/mol.The particle diameter distribution of nanoparticle is 40~200nm.The nanoparticle of the present invention has good bio-compatibility and stability, can be used as pharmaceutical carrier, have slow releasing function, the invention discloses its way and purposes. |
priorityDate | 2014-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.