http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104614456-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
filingDate | 2015-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104614456-B |
titleOfInvention | A kind of method simultaneously detecting blood plasma midbrain Xintong capsule main component |
abstract | The invention provides a kind of liquid chromatography tandem mass spectrometry (HPLC MS/MS) and detect plasma sample midbrain Xintong capsule main component Paeoniflorin, β ecdysterone, amarogentin, Mulberroside A, caffeic acid, forulic acid, tanshin polyphenolic acid B, Astragaloside IV, formononetin, Cryptotanshinone, the method for tanshinone IIA simultaneously.In described liquid chromatogram, flowing is made up of acetonitrile and the aqueous formic acid that volume fraction is 0.1%, uses gradient elution.Described mass spectrum uses negative ions to be switched fast analytical model, MRM scan mode.Measure after being administered cerebral ischemic capsule, the blood concentration situation of change of these several main components in rat plasma simultaneously.Methodological study result shows that set up method meets vivo biodistribution sample determination requirement, and method sensitivity is good, and specificity is strong, stable, reliable, the detection of the relatively low material of Optimum Contents. |
priorityDate | 2015-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.