http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104611784-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01D1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01D5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F8-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F1-10 |
| filingDate | 2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104611784-B |
| titleOfInvention | Load Docetaxel prepared by high-voltage electrostatic spinning contains nanopore network fiber and application thereof |
| abstract | Load Docetaxel fiber Han nanopore network prepared by high-voltage electrostatic spinning disclosed by the invention is by poly (propylene carbonate), polycaprolactone and Docetaxel in mass ratio 45～98:1～40:1～15 and in terms of first three material gross mass 0.2～the conducting metal salt blend of 0.5%, it is prepared from through high-voltage electrostatic spinning method, its electromicroscopic photograph shows that this fiber is to be made up of the nanopore network being mutually communicated in a large number, and specific surface area is 130 211m 2 /g.The invention also discloses the application in After gliomas operation chemotherapy of this fiber.Fiber not only its surface and inside that the present invention provides can form the nanopore network being mutually communicated, the specific surface area being greatly increased can also improve rate of release and the Cumulative release amount of carrying medicament DOC, significantly improve medicine intramural invasion in tumor, reach more preferable antitumous effect, also because having good biocompatibility and biodegradability, can use as sustained-release chemotherapy medicine locally in malignant glioma postoperative chemotherapy, and preparation method is simple, controlled. |
| priorityDate | 2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.