http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104611305-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-84 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0004 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
filingDate | 2014-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104611305-B |
titleOfInvention | The Aflatoxin-detofizyme that trypsin-resistant improves |
abstract | The invention discloses a kind of Aflatoxin-detofizyme improved to trypsin-resistant.The present invention is transformed the critical amino acid residues at wild type Aflatoxin-detofizyme three-dimensional structure outer layer position by protein engineering, there is provided a kind of to obtain the ADTZ mutant improved to trypsin-resistant.Mutant Aflatoxin-detofizyme (the ADTZ of the present invention for acting on aflatoxin K221C/K252Q/K278S ), 2.73 times are improved than wild type ADTZ to the resistance of trypsase, its half-life period extends 72 minutes than wild-type enzyme, and other zymologic properties and wild-type enzyme are basically identical. |
priorityDate | 2014-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.