http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104610413-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J51-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J51-00 |
filingDate | 2013-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104610413-B |
titleOfInvention | Prednisolone phosphoric acid ester purifying process |
abstract | The present invention discloses a kind of prednisolone phosphoric acid ester purifying process, belongs to chemical pharmacy field.This technique for raw material with prednisolone phosphoric acid ester crude product, comprises and dissolving with pure water, add sodium hydroxide solution, pH value is adjusted to 10.2-10.4, adds Tai-Ace S 150, make pH value 8.0-8.5, with hydrochloric acid adjust pH to 7.5-7.0, filter after filtration, acidifying leave standstill and obtain prednisolone phosphoric acid ester purified.Adopt this process stream after purifying, crystallization is comparatively white, and to final product quality, particularly turbidity one has larger raising, is conducive to using as high-quality product. |
priorityDate | 2013-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.