| abstract |
The method that the disease of ROR γ mediations is treated the invention provides orphan nuclear receptor ROR γ instrumentalities and by the way that these new ROR γ instrumentalities are administered into the mankind in need or mammal.Particularly, the cyclic compound containing formamide or sulfonamide of offer formula (1), (1 '), (100), (100 '), (200) and (200 ') of the present invention And its mirror image isomerism thing, non-mirror image isomeric compound, compounds tautomeric, N oxides, solvate and pharmaceutically acceptable salt. |