http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104597027-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-65 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65 |
filingDate | 2015-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104597027-B |
titleOfInvention | A kind of method based on Nano silver grain tetrahedron Raman Multiple detection |
abstract | A kind of method based on Nano silver grain tetrahedron Raman Multiple detection, belongs to technical field of analytical chemistry.The present invention is successfully assembled using DNA mediations self-assembly technology and obtains Nano silver grain tetrahedron, utilize tetrahedral special space configuration, by introducing three sections of DNA and three kinds of beacon molecules containing determinand SDM, AFM1, OTA aptamer fragment in Nano silver grain tetrahedron, successfully construct based on the tetrahedral Raman Multiple detection system of Nano silver grain, when there is determinand, tetrahedral steric configuration, which changes, causes the change of Raman signal, and then is detected;The change of three kinds of beacon Molecular Raman signals corresponds to the concentration of three kinds of objects, it is achieved thereby that detecting while to three kinds of object SDM, AFM1 and OTA.This method has high sensitivity and good specificity, and avoids influence of the unordered aggregation of nano-particle to testing result, the advantageously application in Raman sensing detection technology in practice. |
priorityDate | 2015-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.