http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104592338-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 |
filingDate | 2015-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104592338-B |
titleOfInvention | A kind of method for synthesizing symmetric double ribonucleoside triphosphote, four phosphoric acid and five sodium ascorbyl phosphates |
abstract | The invention belongs to the field of chemical synthesis, it is related to a kind of method for synthesizing symmetric double ribonucleoside triphosphote, four phosphoric acid and five sodium ascorbyl phosphates, with 4,5 dicyano imidazoles are activating reagent, respectively using monophosphate, pyrophosphate and triphosphate as nucleopilic reagent, after nucleoside polyphosphates intermediate corresponding with more than twice excessive nucleosides phosphinylidyne piperidines triethylamine salt coupling generation, continue symmetric double nucleoside polyphosphates sodium salt corresponding with the reaction generation of remaining nucleosides phosphinylidyne piperidines in one pot reaction.The inventive method is simple, product separation yield is high. |
priorityDate | 2014-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.