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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
filingDate 2015-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104592225-B
titleOfInvention A kind of synthetic method of formoxyl heteroaryl hydro carbons pharmaceutical intermediate compound
abstract The present invention relates to the synthetic method of formoxyl heteroaryl hydro carbons pharmaceutical intermediate compound shown in a kind of formula (I), Described method includes: in organic solvent, and in the presence of catalyst, oxidant and reaction promoter, formula (II) compound and formula (III) compound react, and obtain formula (I) compound, Wherein, R 1 ‑R 4 It is each independently selected from H, C 1 ‑C 6 Alkyl, C 1 ‑C 6 Alkoxyl, phenyl or nitro.The selection of the method catalyst, oxidant, reaction promoter and reaction substrate and combination, it is achieved thereby that the formylated of specific site, and productivity has good productivity, is with a wide range of applications and potentiality in pharmaceutical intermediate synthetic method field.
priorityDate 2015-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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