Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-50 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-12 |
filingDate |
2015-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2017-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-104592114-B |
titleOfInvention |
Substd quinolines histone deacetylases inhibitor and preparation method and application |
abstract |
The invention discloses a kind of substd quinolines histone deacetylases inhibitor and its preparation method and application, compound has the structure such as formula I.Compound of the invention has stronger inhibitory activity for histon deacetylase (HDAC) (HDACs); can be used to prepare prevention or treat because of the medicine of related mammalian disease caused by histon deacetylase (HDAC) abnormal expression, the invention further relates to the pharmaceutical applications of the composition with general formula I compound. |
priorityDate |
2015-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |