| abstract |
A kind of compound as shown in following formula 1, and its pharmaceutically acceptable salt, ester, hydrate, organic solvent compound, in formula (1), group R 1 To R 17 Separately it is selected from hydrogen, fluorine, chlorine, bromine, iodine, C 1 ‑C 8 Alkyl, C 1 ‑C 8 Alkoxy, carbonyl, hydroxyl, amino, azido, carboxyl and C 1 ‑C 8 Alkylsulfinyl；X is carbon atom or nitrogen-atoms；Y is selected from following group：Singly-bound, C 1 ‑C 8 Alkylidene, C 6 ‑C 20 Arlydene and C 4 ‑C 20 Inferior heteroaryl；N is 5 to 20 integer.Present invention also offers the pharmaceutical compositions comprising the compound and its application in therapeutic field of tumor. |