http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104558086-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 |
| filingDate | 2014-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104558086-B |
| titleOfInvention | A kind of 5 β-3 α, the preparation method of 7 alpha-dihydroxy-6 α-ethyl-cholanic acid |
| abstract | The invention provides a kind of 5 β 3 α, the preparation method of 7 α dihydroxy 6 α ethyl cholanic acids, the method is: in aprotic solvent, under highly basic effect, use halosilanes is by 5 β 3 α ethoxy carbonyloxy group 7 carbonyl cholanic acid methyl ester silanizations, then carries out to mountain aldol reaction, re-uses palladium carbon and hydrogen reducing 5 β 3 α ethoxy carbonyloxy group 6 ethylidene 7 carbonyl cholanic acid methyl ester, hydrolyze again, obtain 5 β 3 α hydroxyl 6 α ethyl 7 carbonyl cholanic acids；Finally use sodium borohydride reduction 5 β 3 α hydroxyl 6 α ethyl 7 carbonyl cholanic acid, obtain 6 ECDCA.Raw material sources used by the present invention are extensive, only need a step silicon ether protection, and technique is simple, and product yield is high. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020119836-A1 |
| priorityDate | 2014-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.