http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104555980-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-157 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01B31-02 |
filingDate | 2014-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104555980-B |
titleOfInvention | A kind of carbon quantum dot based on aspirin and biologic applications thereof |
abstract | Based on the application of the carbon quantum dot of aspirin and cell imaging and anti-inflammatory treatment aspect, belong to Nano medication technical field。It is specifically related to, when hydrazine hydrate solution promotes that aspirin dissolves, utilize microwave heating method to be prepared into the carbon quantum dot with hyperfluorescence character。Carbon quantum dot prepared by the method is highly stable when high salt concentration and physiological pH, maintains blue-fluorescence, and can enter nucleus, cell is carried out effective spike;Also retains the original anti-inflammatory efficacy of aspirin simultaneously, in the acute inflammation model utilizing carrageenin to build, can effectively suppress inflammatory cell to produce;Additionally, prepared aspirin carbon quantum dot toxicity is less, liver function, kidney merit and the internal organs such as the heart, liver,spleen,kidney will not be produced impact by application in vivo, it may be achieved nano material has the target of diagnosis and treatment double effects。 |
priorityDate | 2014-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.