http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104531730-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-40 |
filingDate | 2014-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104531730-B |
titleOfInvention | Clostridium perfringens alpha toxin Humanized single chain antibody 8B |
abstract | The invention discloses clostridium perfringens alpha toxin Humanized single chain antibody 8B, it is screened from phage antibody library Source bioscience, it is the anti-clostridium perfringens alpha toxin antibody in full people source, both the therapeutic effect to neutralize a toxin may be implemented, a variety of side effects of heterogenetic antibody are overcome simultaneously, it eliminates heterogenetic antibody and carries out humanization modified tedious steps and high cost, since single-chain antibody molecules amount is small, internal penetration capacity is strong, it is rapid to reach damaged tissues and the effect of cells play antitoxin, therefore reach economic and efficient dual purpose.Alpha toxin with C.perfringens other types toxin there is certain homology, the antibody drug to be possible to having inhibition and therapeutic effect to other kinds of toxin, also can be used as detection reagent detection clostridium perfringens alpha toxin. |
priorityDate | 2014-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 411.