http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104529884-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-64 |
| filingDate | 2014-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104529884-B |
| titleOfInvention | Green synthetic method for preparation of N-alkyl pyridone |
| abstract | The invention discloses a green synthetic method for preparation of N-alkyl pyridone. According to the method, a hydroxypyridine compound and alcohol undergo selective dehydration N-alkylation under the catalysis of a non-transition metal catalyst, wherein the non-transition metal catalyst is halogenated hydrocarbon; alcohol and the hydroxypyridine compound directly undergo N-selective dehydration under the catalysis of halogenated hydrocarbon so as to obtain an N-alkyl pyridone compound; the usage amount of the halogenated hydrocarbon is 5 to 50 mol%; reaction temperature is 100 to 180 DEG C; reaction time is 6 to 60 hours; and the byproduct is water. The method provided by the invention employs cheap, easily and widely available, stable and low-toxicity alcohol as an alkylating reagent and common halogenated hydrocarbon as the non-transition metal catalyst and directly synthesizes the N-alkyl pyridone compound through highly-selective dehydration N-alkylation without a solvent. The method has low requirements on reaction conditions, a wide application scope and certain research and industrial application prospects. |
| priorityDate | 2014-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.