http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104523639-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 |
| filingDate | 2014-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104523639-B |
| titleOfInvention | Agomelatine tablet and preparation method thereof |
| abstract | The invention discloses an agomelatine tablet of which the formula comprises the following components by weight: 25g of agomelatine crystal form II, 55-70g of lactose, 13-30g of starch, 6-12g of povidone K30, 5-10g of carboxymethyl starch sodium, 1-3g of stearic acid, 0.5-1.5g of magnesium stearate, 0.1-0.5g of silicon dioxide, 4-6g of coating powder, 70-90g of 75% ethanol, 1-2g of potassium gluconate, 1-2g of arabic gum and 1-2g of magnesium citrate. The potassium gluconate, Arabic gum and magnesium citrate are added into the formula of the agomelatine tablet provided by the invention to adjust the dissolution rate of the tablet, so that the coated tablet has good dissolution behavior and stronger stability. |
| priorityDate | 2014-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.