http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104513808-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-079 |
| filingDate | 2013-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104513808-B |
| titleOfInvention | A kind of rat retina microglia system of the high chemotaxis of retina |
| abstract | The invention belongs to technical field of microbe cell line, it is related to rat retina microglia system and its method for building up of a kind of high chemotaxis of retina.This cell line is mouse cell, has the gene difference less than 1% with the retinal microglia of originally culture and is not related to major function albumen；Energy self duplication, continuous passage；Monocytes/macrophages surface antigen CD11b (OX42) can be expressed, ED1 (OX6), can the pro-inflammatory cytokines such as TNF secretion-а, IL-1 β and iNOS with phagocytic activity and under the stimulation of LPS；It can be raised to retinal damage position and be survived by efficiently and directionally after transplanting in vivo, further promote photoreceptor survival.Cell line of the present invention can be used for the study on prevention of retinal photoreceptor degenerative disease, and can be used as the pharmaceutical carrier from periphery-maincenter (retina). |
| priorityDate | 2013-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.