http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104513216-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe0127bac6f67758b3389e7f761352e6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-351 |
| filingDate | 2014-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95814cea61a179f38b2e1a8470ae57e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3883c401e3650aa90e5bd48ae9d13c78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a46f35139262c02f886e2a0aaad2045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_376ce3581f4c8436ad0efa2bf2be341d |
| publicationDate | 2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104513216-A |
| titleOfInvention | A kind of hydroxysafflower yellow A analogue and its preparation and application |
| abstract | The present invention provides a kind of hydroxy safflower yellow A analogue, by mixing compound (II) and 2,4,6-trihydroxybenzaldehyde and sodium hydroxide aqueous solution under argon, stirring, refluxing, using ethyl acetate Extract, filter, and concentrate under reduced pressure to obtain compound (III), then add D-glucose and water to mix, stir, add Sc(OTf)3 under argon, heat the oil bath to reflux, extract with ethyl acetate, concentrate the aqueous phase, and leave The substance was dissolved in methanol, filtered, and the methanol phase was concentrated to dryness. Compared with safflower yellow, the compound provided by the invention has better anticoagulant effect in vivo and in vitro, has higher practical value and development prospect, and can be used in the preparation of anticoagulant drugs. The structural formula of the compound of the present invention: . |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106478560-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113200843-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113200843-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106478560-B |
| priorityDate | 2014-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.