| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-77 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6849
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 |
| filingDate |
2013-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_920790565788e6f067f5fb49d7772791
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fbefe5341d20a8dff333a57fe8c956a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78b796035d6f6840b2ee304a63859106 |
| publicationDate |
2015-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-104507537-A |
| titleOfInvention |
Compositions and methods for modulating CAR T cells |
| abstract |
The present invention provides a method of inhibiting healthy tissue depletion during CAR T cell therapy comprising administering to a subject receiving CAR T cell therapy a drug-molecule conjugate comprising a drug and a molecule that binds to a protein expressed on the surface of the T cell. CAR. The present invention relates to binding of the conjugate to the CAR resulting in internalization of the conjugate into cells and drug-mediated cell death. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109476722-A |
| priorityDate |
2012-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |