http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104498437-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate | 2014-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104498437-B |
| titleOfInvention | The barrier defect epidermis model and construction method of a kind of vitro recombination |
| abstract | The present invention relates to the barrier defect epidermis model and its construction method of a kind of vitro recombination, for the defect model in successful epidermal cell is transfected, the expression quantity of loricrin gene level is the 40% of normal cell；With the model of the cell construction, loricrin content drops to the 35% of normal model；For the defect model compared with normal model, phantom thicknesses are the 60% of normal model；The living cells number of plies is 34 layers；Model vitality test OD values maintain 0.8 1.0.The construction method of the barrier defect epidermis model, include the preparation of epidermal cell, the dimensional culture of the preparation of defect culture medium and barrier defect epidermis model of the expression of loricrin gene defect.The present invention verifies significant using the epidermis alternative model of RNA perturbation techniques structure barrier defect for exploitation barrier prosthetic cosmetics and cosmetic industry. |
| priorityDate | 2014-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 118.