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filingDate 2014-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104490489-B
titleOfInvention Method for preparing tissue engineering blood vessel based on 3D bioprinting technology
abstract The invention provides a method for preparing a tissue engineering blood vessel based on a 3D (3-Dimensional) bioprinting technology. The method comprises the following steps:alternately printing a blood vessel shape by virtue of a high-polymer material and a human renascent skin fiber cell column, and removing the high-polymer material after fusion to structure a tissue engineering blood vessel; filling late-outgrowth endothelial progenitor cells into the blood vessel, and performing in-vitro dynamic culturing for 7 days in a bioreactor to obtain a differentiated tissue engineering blood vessel, wherein the high-polymer material is one of pluronic F127, poly(N-isopropylacrylamide), methyl cellulose and sodium alginate. The blood vessel obtained by the method is high in biocompatibility and higher in mechanical property, thrombus formation resistant and platelet adhesion resistance, and can be used for repairing and replacing a damaged or disease blood vessel.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110373324-A
priorityDate 2014-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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