http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104479671-B

Outgoing Links

Predicate Object
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
filingDate 2014-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104479671-B
titleOfInvention For detecting rhodamine B pair sulphur class fluorescent probe and the preparation and application of aqueous media and mercury ion in cell
abstract The present invention discloses the two sulphur class fluorescent probe of a kind of rhodamine B for detecting aqueous media and mercury ion in cell and preparation and application. The two sulphur class fluorescent probe of this rhodamine B is in an aqueous medium by the chelating ligands effect to mercury ion, rhodamine fluorescence probe Middle molecule closed loop is opened, thus produce fluorescence, the starting point concentration of its fluorescence intensity and mercury ion has good linear relationship, and is attended by probe solution from colourless to the bore hole visual color change of pink; Meanwhile, the single-minded selectivity that mercury ion is very high is shown; In addition, this fluorescent probe has good biocompatibility and cell permeability, and lower cytotoxicity can be used for the detection of mercury ion in cell, and shows good mercury ion detecting sensitivity. Its preparation take rhodamine B as raw material, and by rhodamine B acid chloride intermediate obtained with phosphorus oxychloride effect, this acid chloride intermediate obtains the mercury ion probe with highly sensitive and highly selective more further with two sulphur intermediate condensation.
priorityDate 2014-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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