http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104479671-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
filingDate | 2014-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104479671-B |
titleOfInvention | For detecting rhodamine B pair sulphur class fluorescent probe and the preparation and application of aqueous media and mercury ion in cell |
abstract | The present invention discloses the two sulphur class fluorescent probe of a kind of rhodamine B for detecting aqueous media and mercury ion in cell and preparation and application. The two sulphur class fluorescent probe of this rhodamine B is in an aqueous medium by the chelating ligands effect to mercury ion, rhodamine fluorescence probe Middle molecule closed loop is opened, thus produce fluorescence, the starting point concentration of its fluorescence intensity and mercury ion has good linear relationship, and is attended by probe solution from colourless to the bore hole visual color change of pink; Meanwhile, the single-minded selectivity that mercury ion is very high is shown; In addition, this fluorescent probe has good biocompatibility and cell permeability, and lower cytotoxicity can be used for the detection of mercury ion in cell, and shows good mercury ion detecting sensitivity. Its preparation take rhodamine B as raw material, and by rhodamine B acid chloride intermediate obtained with phosphorus oxychloride effect, this acid chloride intermediate obtains the mercury ion probe with highly sensitive and highly selective more further with two sulphur intermediate condensation. |
priorityDate | 2014-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.