http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104473915-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-222 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-222 |
| filingDate | 2014-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104473915-B |
| titleOfInvention | Sivelestat is as the application for the treatment of epilepsy medicament |
| abstract | The present invention relates to the sivelestat application as treatment epilepsy medicament.Sivelestat can reduce inflammatory mediator, protection neuron, but its most protected effect of brain tissue impairment caused in epilepsy, has no relevant report the most both at home and abroad.The invention provides sivelestat as treatment epilepsy medicament application, described sivelestat by suppression High mobility group box-1 and the expression of neutrophil elastase, stop High mobility group box-1 migration, reduce impaired brain cell inflammatory reaction, reduce serum S100 β content and as antiinflammatory, antiepileptic medicine.Sivelestat can form protection blood brain barrier, reduces epilepsy inflammatory reaction, reduces the quantity of damage hippocampal neuron, produces the protective effect to impaired brain neuron. |
| priorityDate | 2014-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.