http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104448161-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F290-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 |
filingDate | 2014-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104448161-B |
titleOfInvention | Organic composite hydrogel cross-linked by modified gelatin nano-microsphere and preparation method of organic composite hydrogel |
abstract | The invention provides an organic composite hydrogel cross-linked by a modified gelatin nano-microsphere and a preparation method of the organic composite hydrogel. Specifically, the preparation method comprises the following steps: preparing a modified gelatin nano-microsphere by virtue of a two-step solvent removal process, then respectively dissolving an acrylamide monomer and the modified gelatin nano-microsphere in de-ionized water and stirring in an inert atmosphere for 5-30min; adding a catalyst, stirring in the inert atmosphere for 5-10min, and adding an initiator; carrying out a free radical polymerization reaction at minus 40-40 DEG C for 12-48hr; and soaking a reactant in de-ionized water at 20 DEG C, replacing the de-ionized water once every other 5-8hr, and keeping for 48-72hr to obtain the organic composite hydrogel. The method disclosed by the invention is simple in process and controllable in condition, and the prepared organic composite hydrogel integrates the characteristics of a nano composite material and covalent cross-linking and has the characteristics of being good in biocompatibility, mechanical property, macro-porous property, rapid swelling property and the like; and the organic composite hydrogel can be widely applied to the biomedical materials of biological scaffold, cell culture, medicine controlled release, tissue engineering and the like. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102440646-B1 |
priorityDate | 2014-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.