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filingDate 2014-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7b61670b626e5bce6dd2417f3d3316b
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publicationDate 2015-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104447916-A
titleOfInvention Method for synthesizing fraxinol glycosides
abstract The invention relates to a method for synthesizing fraxinol glycosides and belongs to the technical field of a synthesis process for organic compounds. The synthetic route of the method is as follows: (A) 2,6-dimethoxy-1,4-p-benzoquinone to 2,6-dimethoxy hydroquinone; (B) 2,6-dimethoxy hydroquinone to 1,3-dimethoxy-2,5-dibenzyloxybenzyl; (C) 1,3-dimethoxy-2,5-dibenzyloxybenzyl to 2,4-dimethoxy-3,6-dibenzyloxybenzyl methanal; (D) 2,4-dimethoxy-3,6-dibenzyloxybenzyl methanal to 2,4-dimethoxy-3,6-dihydroxy benzaldehyde; (E) 2,4-dimethoxy-3,6-dihydroxy benzaldehyde to fraxinol; (F) fraxinol to fraxinol glycosides. The method has the benefits that along with the decreasing of plant resources, the fraxinol glycosides being extracted from fraxinus mandshurica barks or leaves is difficult to meet the needs of market, but the method solves the problem of great needs of market; the molecular weight coumarin compounds is relatively small, synthesis is relatively simple, and the bioavailability is high.
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type http://data.epo.org/linked-data/def/patent/Publication

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