| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac3eca7fa2f8ecd6ea05588b14520fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 |
| filingDate |
2013-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10765cf7ebfa8d22d45a8f3fbfa2b98f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_278f029117790aca3df2c1ee179ebc8b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be3ef0edf619188f9b4657d68f08d5f8 |
| publicationDate |
2015-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-104447823-A |
| titleOfInvention |
The preparation method of 4-dihydroxyboryl-L-type phenylalanine |
| abstract |
The present invention provides a preparation method of 4-dihydroxyboryl-L-type phenylalanine, which comprises: (S)-4-halophenylalanine with protected amine end represented by formula (I) Reaction with a boronating agent and an organolithium compound to obtain a reaction mixture comprising (S)-4-dihydroxyboryl phenylalanine protected at the amine end shown in formula (II), and R is protected base; Isolate the (S)-4-dihydroxyboryl phenylalanine protected at the amine end from the reaction mixture; and deprotect the protected (S)-4-dihydroxyboryl phenylalanine at the amine end Acid protecting group to make 4-dihydroxyboryl-L-phenylalanine. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112574245-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019219044-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110498810-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110498810-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10323046-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108299479-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108373479-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017028751-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108373479-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108218903-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108218903-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2688676-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108484652-A |
| priorityDate |
2013-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |