http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104447733-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-427 |
| filingDate | 2015-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104447733-B |
| titleOfInvention | 1-benzyl-2-pyrrolidinone-4-amide compounds and their preparation methods and applications |
| abstract | The invention discloses a 1-benzyl-2-pyrrolidinone-4-amide compound represented by the following general formula I, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 or R 10 are each independently unsubstituted C 1-4 alkyl, unsubstituted C 1-3 alkoxy, halogen, sulfamoyl, nitro, hydrogen, or halogen, nitro , C 1-3 alkyl, C 1-2 alkoxy, C 1-4 alkyl substituted with 1 to 3 substituents, or halogen, nitro , C 1-3 alkyl, C 1-3 C 1-3 alkoxy group substituted by 1 to 3 substituents selected from 2 alkoxy groups; said halogen is fluorine, chlorine or bromine. The invention also discloses the preparation method and application of the above compound. The compound of the present invention can inhibit tyrosine kinase signal transduction, inhibit undesirable cell proliferation and angiogenesis, and especially have remarkable curative effect on diseases such as tumors. |
| priorityDate | 2015-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.