http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104447702-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 |
filingDate | 2014-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104447702-B |
titleOfInvention | A kind of amido replaces Bouchardatine derivant and its preparation method and application |
abstract | The invention discloses a kind of amido and replace Bouchardatine derivant and its preparation method and application, shown in described derivant structure formula such as formula (I): Wherein: R is (CH 2 ) n R 1 , n=0,1,2,3 or 4;R 1 For substituted-phenyl, heterocyclic radical, substituted-amino, C 1‑6 Fatty alkyl, C 3‑6 Cycloalkyl or hydroxyl;What the amido that the present invention provides replaced that Bouchardatine derivant can significantly block PECTORAL LIMB SKELETON 3T3 L1 is divided into fat process, reduce the lipid in 3T3 L1 adipose cell and HepG 2 intracellular cholesteryl content, there is anti-obesity and alleviate fatty liver generation effect. |
priorityDate | 2014-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.